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Updated: Sep 14, 2026
Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Botox Complications and Satisfaction Outcomes Following Botulinum Toxin Type A Facial Injections: A Prospective Study
Raul Daniel Chioibaș1, Dan Lolos2, Andreea Raissa Hojda3
1Emergency Discipline, "Victor Babes" University of Medicine and Pharmacy, Department of Surgery, Romania, Timisoara.
Introduction:
Botulinum toxin type A is widely used for facial rejuvenation, but prospective real-world data integrating safety and patient-reported outcomes (PROs) remain limited.
Objectives And Hypotheses:
To evaluate complication rates, patient satisfaction, and predictors of satisfaction following standardized upper-face injections.
Study Design:
Prospective, single-center cohort study.
Methods:
A total of 489 patients undergoing 2,012 procedures were treated using a standardized protocol. Clinically significant complications were recorded over 4 weeks. PROs were assessed using a customized 20-item questionnaire.
Results:
The per-patient complication rate was 13.1%, while the per-procedure rate was 3.3%. Most complications were mild and resolved without sequelae. Overall, 94.1% of patients reported improvement, and 79.6% achieved ≥ 9/10 satisfaction. Younger age, female sex, and lower complication severity were associated with higher satisfaction.
Conclusion:
Standardized botulinum toxin protocols provide low complication rates and high patient satisfaction. Combined reporting of safety and PROs supports reproducible and clinically relevant evaluation.
