Cystoid macular edema following travoprost intracameral implant

To describe a case of bilateral cystoid macular edema (CME) that developed following intracameral travoprost implantation, which then resolved after explantation, and to review the association of CME with prostaglandin analogues (PGA).

The patient developed CME after intracameral travoprost implantation in each eye. An extensive work up including blood work and aqueous biopsy did not reveal other inflammatory etiologies. Explantation of the travoprost led to resolution of the CME in each eye, suggestive of a temporal association of the implant and the CME.

The association of CME with intracameral PGA might differ from previously reported associations of CME with topical PGA, because intracameral medications provide a sustained dose closer to the retina. Surgeons should consider PGA as a possible etiology in cases of post-procedural CME.