Related Experiment Video
Updated: Sep 15, 2026

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
Published on: April 19, 2017
First case report of onychomycosis caused by Exophiala alcalophila
Lili Rueda-Jaime1, Leticia Sopó-Prada2, Carolina Firacative3
1Clinical and Infectious Dermatology Research Group, Universidad El Bosque, Bogota, 110121, Colombia.
Abstract:
A 46-year-old woman from Colombia, without any medical comorbidities, presented with marked yellowish discoloration of both big toenails, suggestive of onychomycosis, and malalignment of the nail plate. Culture of nail scrapings grew dark-pigmented, mucoid, yeast-like colonies identified as Exophiala alcalophila by ITS sequencing. Broth microdilution identified the isolate as resistant to fluconazole and the echinocandins. The patient refused antifungal treatment. This case highlights the importance of black yeast-like fungi as etiological agents of onychomycosis.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Candidiasis
Fungal Phylum Microsporidia
Fungal Phylum Ascomycota
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...