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In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
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Convergent evolution of viral nucleases targeting cyclic dinucleotides

Zichen Li1,2, Leiliang Zhang1,2

  • 1Department of Infectious Diseases, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Plos Pathogens
|September 15, 2026
PubMed

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