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Updated: Sep 17, 2026
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Transition From Systemic Sclerosis to Interstitial Lung Disease: Methodological Considerations
Shiying Fang1, Yafei Ren2, Yuhong Shi3
1S. Fang, MD, Department of Rheumatology and Immunology, Guilin Medical University, Guilin City.
The Journal of Rheumatology
|September 15, 2026
Abstract:
We have read with great interest the article by Rodríguez Viera and colleagues1 employing a systematic review approach to identify soluble mediators in bronchoalveolar lavage fluid (BALF) that are differentially expressed between patients with systemic sclerosis (SSc)-associated interstitial lung disease (SSc-ILD) and those with SSc alone. The study underscores the central role of pulmonary epithelium-fibroblast interactions in driving the transition from SSc to SSc-ILD.
