Related Experiment Video
Updated: Sep 17, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Transcatheter treatment of aortic coarctation
Victor Arévalos1, Anthony Salazar-Rodríguez2, Guillermo Velázquez2
1División de Medicina Cardiovascular, Hospital de Clínicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay.
Abstract:
Aortic coarctation is a congenital disease that consists of the narrowing of the thoracic aorta, leading to distal blood flow obstruction. Significant aortic coarctation is associated with hypertension and distal hypoperfusion, with a poor prognosis without intervention. Initially, treatment was surgical; however, less invasive techniques such as percutaneous balloon angioplasty later emerged and proved effective in selected patients. The introduction of stent implantation significantly improved the outcomes, making percutaneous repair the preferred option, especially in adolescents and adults. However, immediate and long-term complications persist, which has driven research efforts aimed at improving the safety and efficacy profile. Modern strategies now focus on advanced stent designs, offering better delivery profiles and high redilatation potential. Gaps in knowledge remain, and data from studies with longer follow-up will be essential to further elucidate disease progression in these patients. This review aims to offer a comprehensive overview of these percutaneous procedures, discussing recent advancements, clinical outcomes, and future perspectives.
Related Concept Videos
Aortic Regurgitation III: Medical Management
Aneurysm III: Interprofessional Care
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
