Metagenomic Next-Generation Sequencing Analysis of Pathogens in Infected Wounds from Dog and Cat Bites - China,...

Dog and cat bites frequently develop polymicrobial wound infections requiring prompt and appropriate antimicrobial treatment. However, conventional culture-based methods often fail to identify all pathogens, particularly anaerobic and fastidious microorganisms.

This study used metagenomic next-generation sequencing (mNGS) to analyze infected dog- and cat-bite wounds. Distinct microbial profiles were identified between dog and cat bites, and between domestic and stray animals. Anaerobes were predominant in both groups.

These findings highlight the value of mNGS and support empirical antimicrobial strategies to improve infection management and reduce complications.