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Updated: Sep 17, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Transcatheter Edge-to-Edge Mitral Valve Repair for Severe Degenerative Mitral Regurgitation With Coexisting Cor
Shicheng Li1, Yubao Hu1, Jie Shen2
1Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; Institute of Cardiovascular Sciences, Guangxi Academy of Medical Sciences, Nanning, China.
Background:
Cor triatriatum sinistrum (CTS) is a rare congenital malformation, and its coexistence with degenerative mitral regurgitation (MR) in older adults is exceptionally rare and creates substantial technical challenges for transcatheter interventions.
Case Summary:
We report a 78-year-old woman presenting with progressive dyspnea, palpitations, and lower limb edema secondary to severe MR caused by posterior mitral leaflet prolapse. Preprocedural imaging incidentally identified a complete, nonfenestrated CTS membrane. Three clips were sequentially implanted at the prolapse site, downgrading MR from severe to trace. The final mean transmitral gradient was 3 mm Hg. The patient achieved rapid symptom resolution and was discharged 7 days postprocedure.
Discussion:
This case establishes the feasibility of mitral transcatheter edge-to-edge repair in patients with CTS through meticulous preprocedural planning and controlled transmembranous access. It broadens the therapeutic landscape for anatomically complex, surgically prohibitive older adults with valvular disease.
Take-Home Message:
The mitral transcatheter edge-to-edge repair is feasible and safe in MR with CTS.
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