Related Experiment Video
Updated: Sep 18, 2026

Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
Published on: September 26, 2016
Symmetry-based pulsed DNP and EPR sequences
Zhenfeng Pang1, Giuseppe Sicoli2, Benoit Driesschaert3
1Chimie Physique et Chimie du Vivant (CPCV), UMR 8228, Département de Chimie, École Normale Supérieure, PSL Université, Sorbonne Université, CNRS, 75005 Paris, France.
Abstract:
Pulsed microwave irradiation provides more versatile control over spin dynamics than continuous-wave (CW) methods. This study adapts symmetry-based dipolar recoupling sequences, which are originally designed for magic angle spinning (MAS) NMR, to exploit electron-nuclear interactions for dynamic nuclear polarization (DNP) and pulsed electron paramagnetic resonance (EPR). Using the trityl radical OX071 at X-band (0.35 tesla), phase-modulated microwave pulses were synchronized with the nuclear Larmor period. Experimental results show effective DNP performance and electron-nuclear distance measurements in EPR, consistent with numerical simulations and theory. This work shows that many MAS NMR pulse sequences can be adapted to static pulsed EPR and DNP with minor modifications. This cross-disciplinary approach provides a versatile platform for designing optimized, application-specific magnetic resonance methodologies across various field strengths, subject to instrumental capabilities.
Related Concept Videos
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
2D NMR: Overview of Homonuclear Correlation Techniques
COSY90 is the standard two-dimensional (2D) COSY experiment that...
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
¹H NMR: Interpreting Distorted and Overlapping Signals
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...

