Related Experiment Video
Updated: Sep 18, 2026

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
Host genes associated with infectious diseases in livestock: implications for disease-resistance breeding and disease
Wei Zeng1, Changfan Zhou1, Fan Chen1
1Key Laboratory of Animal Embryo Engineering and Molecular Breeding of Hubei Province, Institute of Animal Sciences and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan 430070, China.
Abstract:
As global demand for animal protein continues to rise, higher stocking densities have increased the risk of infectious disease outbreaks. Conventional control strategies, including vaccination, antimicrobial use, and biosafety management, are increasingly constrained by pathogen evolution, antimicrobial resistance, and the need for sustained interventions. Improving host genetic resistance provides a complementary approach to disease prevention by reducing susceptibility to infection and limiting pathogen spread within animal populations. This review summarizes recent progress in identifying host genes involved in pathogen infection in livestock, focusing on those that influence host susceptibility or resistance. Representative examples of disease-resistant livestock are discussed to illustrate the translational potential of these genes. We also evaluate current challenges and biosafety considerations associated with the use of disease-resistant livestock, thereby supporting the integration of disease-resistance breeding into disease prevention strategies.
More Related Videos
12:53Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
Published on: May 19, 2018
07:56Generation of a Bovine Primary Enteroid-Derived Two-Dimensional Monolayer Culture System for Applications in Translational Biomedical Research
Published on: April 5, 2024
Related Concept Videos
Clinical Significance of Antibiotic Resistance
The Central Dogma
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
Reservoir of Infection
Antibiotic Selection
Recombinant DNA Technology
Types of Genetic Transfer Between Organisms