Related Experiment Video
Updated: Sep 18, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
The Dermoscopic Step-Like Border in Circumscribed Hypokeratosis: A Case Involving the Finger and Literature
Takuya Nagata1, Yasuaki Ikuno1, Masahiro Yamada1
1Department of Dermatology, Shiga University of Medical Science, Otsu, Japan.
Abstract:
Circumscribed hypokeratosis is a rare acquired disorder characterized clinically by a sharply demarcated, slightly depressed erythematous patch and histopathologically by abrupt thinning of the stratum corneum. Although initially described on the palm, similar lesions have been reported on the sole, fingers, and other acral sites, generating site-based terms such as circumscribed palmar, plantar, acral, and digital hypokeratosis. Across these presentations, peripheral dermoscopic findings have been variously described as stair-step, step-ladder, rim-like, or geological-strata appearances; however, their consistency across acral sites and their significance relative to other dermoscopic findings have not been specifically reappraised. Here, prompted by a finger lesion with a distinct dermoscopic step-like border, we reappraised previously reported cases with dermoscopic documentation to assess the consistency of this border finding across acral sites and its significance relative to other dermoscopic features. Among 24 previously reported dermoscopy-documented cases, a step-like peripheral border was identified in 22, whereas associated dermoscopic findings varied considerably among reports. The present dorsal finger case further illustrates that this border phenomenon can occur outside classical palmoplantar presentations. These observations suggest that peripheral border architecture may represent a more consistently reported dermoscopic feature than any single associated finding and may aid recognition of circumscribed hypokeratosis.
Related Concept Videos
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Desmosomes
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...

