Related Experiment Videos
An Uncommon Twist: Intussusception as a Rare Manifestation of Extramedullary Myeloma
Quinn E1,2, Edwards Murphy A1,2, Duggan W1,2
1Department of Surgery, Tallaght University Hospital, Tallaght, D24 NR0A, Dublin, Ireland, tallaghthospital.ie.
Abstract:
We present the case of a 69-year-old female with relapsed multiple myeloma (MM) who presented acutely with small bowel obstruction secondary to a jejunal intussusception. Despite a trial of conservative management the obstruction did not resolve and surgical intervention was required. Laparoscopic-assisted small bowel resection with primary anastomosis was performed. Histopathological examination revealed an extramedullary plasmacytoma with anaplastic features as the lead point of the intussusception. This case outlines the successful management of a rare but important oncological emergency and underscores the importance of considering extramedullary plasmacytoma in the differential diagnosis of bowel obstruction in patients with MM.
Related Concept Videos
Intestinal Obstruction I: Introduction
Diverticular Disease of the Colon
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Appendicitis
Esophageal Varices-I: Introduction
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...