Related Experiment Video
Updated: Sep 19, 2026
Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
Published on: July 19, 2016
DWI-based comparison of thrombogenicity between Surpass Evolve and Surpass Elite flow diverters: an IPTW-adjusted
Kang U Kim1, Jung-Jae Kim1, Keun Young Park1
1From the Department of Neurosurgery (K.U.K.), Armed Forces Goyang Hospital, Goyang, Department of Neurosurgery (J.-J.K., K.Y.P., Y.B.K., H.J.H.), Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Background And Purpose:
Surpass Elite (SEl) incorporates optimized device geometry and a surface modification strategy called surface neutralization. We conducted a retrospective cohort comparison of SEl-FDs and Surpass Evolve (SEv)-FDs to compare the incidence and burden of early postprocedural DWI-positive lesions as surrogate markers of thromboembolic injury.
Materials And Methods:
This study included patients treated with SEl-FDs or SEv-FDs at two tertiary hospitals between November 2019 and February 2026. We examined the rates of patient with DWI-positive lesions and the number of lesions between the two groups using inverse probability of treatment weighting (IPTW) analysis. Furthermore, we performed logistic regression for risk factor analysis.
Results:
Of 149 patients, 101 were treated with SEv-FDs and 48 with SEl-FDs. After IPTW adjustment, an adequate balance was observed for all covariates. When comparing the two groups, the incidence of DWI-positive lesions differed between SEv-FD and SEl-FD (SEv-FD, 64.1% vs SEl-FD, 44.2%); the odds of DWI-positivity were 56% lower in the SEI FD group, and the difference was statistically significant (odds ratio [OR]: 0.44; 95% confidence interval [CI]: 0.20-0.99, P = 0.048). The mean number of lesions was lower in SEl-FD than in SEv-FD group (SEv-FD, 8.69 vs SEl-FD, 6.02), but the difference did not reach statistical significance (incidence rate ratio [IRR]: 0.69, 95% CI: 0.45-1.06, P = 0.091). In multivariable logistic regression, the device was the only significant risk factor for DWI-positive lesions(OR: 0.41, 95% CI: 0.19-0.87, P = 0.02).
Conclusions:
SEl-FDs showed a significantly lower incidence of DWI-positive lesions and a lower number of lesions. This suggests that thromboresistance was improved in SEl-FD compared with SEv-FD.
