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Intravenous Ketamine for Treatment-Resistant Depression: A Case Report From a Public Hospital in Argentina
Micaela Dines1,2, Paloma Bamondez1,3, Micaela Montenegro4
1Drs. Dines, Bulacia, Bamondez, and Diaz are with the Mental Health Section, Department of Medicine, Hospital General de Agudos Dr. Juan A. Fernandez, Buenos Aires, Argentina.
Abstract:
Treatment-resistant depression (TRD) is a severe form of depression associated with high rates of disability and suicide, underscoring the need for effective therapeutic alternatives. In recent years, subanesthetic intravenous (IV) ketamine has emerged as a promising intervention due to its rapid antidepressant and antisuicidal effects. This report describes the case of a 41-year-old male patient with TRD treated with IV ketamine at a public hospital in Argentina-the first such reported case in this setting. We detail the diagnostic process, treatment protocol, outcomes, and practical considerations in implementing this novel therapy within a public health system.
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