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Updated: Sep 21, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Oncoaesthetic Breast Reconstruction After Mastectomy Improves Patient Satisfaction and Aesthetic outcomes
Michele Riccio1, Nicola Zingaretti2, Angelica Aquinati1
1Department of Reconstructive Surgery and Hand Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy.
Background:
Immediate implant-based breast reconstruction has evolved toward an onco-aesthetic strategy integrating oncologic safety, aesthetic optimization, bilateral balance, and patient-centered outcomes. This study evaluated the clinical, aesthetic, and patient-reported outcomes of an integrated onco-aesthetic reconstructive approach following mastectomy.
Methods:
This retrospective single-center cohort included consecutive patients undergoing immediate implant-based breast reconstruction within a standardized onco-aesthetic framework. Surgical planning incorporated individualized skin-envelope management, implant selection, and selective contralateral symmetrization. Patient-reported outcomes were assessed using the BREAST-Q Reconstruction Module, while aesthetic results were independently evaluated using the Harris photographic scale. Bilateral aesthetic outcomes and postoperative complications were also analyzed.
Results:
Fifty-six patients were included; 24 (42.9%) underwent immediate contralateral symmetrization. Significant improvements were observed in BREAST-Q Satisfaction with Breasts (+ 34.9 points), Psychosocial Well-being (+ 20.7), Sexual Well-being (+ 33.5), and Physical Well-being: Chest (+ 19.0) (all P < .001) Good-to-excellent physician-rated aesthetic outcomes were achieved in 35/56 patients (62.5%), and Harris aesthetic quality strongly correlated with postoperative Satisfaction with Breasts (Spearman's ρ = 0.904, P < .001) Contralateral symmetrization was not independently associated with postoperative satisfaction after accounting for achieved aesthetic quality. Postoperative complications occurred in 12/56 patients (21.4%), with implant removal in 3/56 (5.4%) and implant retention of 94.6%.
Conclusions:
An integrated onco-aesthetic approach was associated with substantial improvements in patient-reported outcomes, favorable aesthetic results, and high implant retention. Patient satisfaction was more closely related to achieved aesthetic quality than to contralateral symmetrization itself, supporting individualized bilateral reconstructive planning.