Related Experiment Video
Updated: Sep 21, 2026

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
Published on: May 7, 2019
Declining allocation out of sequence is associated with fewer kidneys recovered and transplanted
Shin Lin1, Aaron M Delman2, Gregory R Martens2
1Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA, USA.
Abstract:
Allocation out of sequence (AOOS) increased after Kidney Allocation System 250 (KAS250) and declined during heightened regulatory and public scrutiny beginning in August 2024. In 2025, deceased donor kidney recovery and transplant volume also decreased for the first time after KAS250. Because the donor pool had been shifting toward higher KDRI donors, we asked whether the decline in kidney recovery during this period exceeded that predicted by KDRI, donor type, and seasonality. Using the pre-August 2024 relationship between KDRI, donor type, seasonality, and kidney recovery, a donor-level model estimated expected recovery among the observed post-August 2024 donors. The model predicted 870 more kidney recoveries than were observed. This difference coincided with declining AOOS but could also reflect unmeasured donor characteristics and other changes occurring at the same time. Under alternative post-recovery utilization assumptions, the model-estimated recovery difference corresponded to approximately 360 to 630 potential additional transplants. The highest KDRI kidneys also experienced the greatest declines in recovery and increases in cold ischemic time. These findings document concurrent national trends and support further evaluation of placement pathways for hard-to-place kidneys as the donor pool shifts toward higher KDRI.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
Acute Kidney Injury II: Pathophysiology
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Acute Kidney Injury I: Introduction
