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Updated: Sep 21, 2026

A Simple and Efficient Method for In Vivo Cardiac-specific Gene Manipulation by Intramyocardial Injection in Mice
Published on: April 16, 2018
RETRACTION: Inhibitory Effect of Melatonin on Necroptosis via Repressing the Ripk3-PGAM5-CypD-mPTP Pathway Attenuates
Retraction:
H. Zhou, D. Li, P. Zhu, Q. Ma, S. Toan, J. Wang, S. Hu, Y. Chen, and Y. Zhang, "Inhibitory Effect of Melatonin on Necroptosis via Repressing the Ripk3-PGAM5-CypD-mPTP Pathway Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury," Journal of Pineal Research 65, no. 3 (2018): e12503, https://doi.org/10.1111/jpi.12503. The above article, published online on 28 May 2018, in Wiley Online Library (https://onlinelibrary.wiley.com/) has been retracted by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley and Sons Ltd. The retraction has been agreed upon following an investigation into concerns raised by a third party, which revealed inappropriate duplications of image panels of Figures 2A, 4A and 7A between this and other articles that were published either around the same time or later by different author groups, depicting different experimental conditions. Further review identified additional issues, including undisclosed splicing in Figure 1J, 4B and 5I, as well as image section insertions in Figure 4A and E. As a result, the editors have lost confidence in the integrity of the data and consider the conclusions of the manuscript to be substantially compromised. The authors and their institution were informed of these concerns and the retraction decision, but remained unresponsive.