Related Experiment Video
Updated: Sep 21, 2026

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
Metastasis of Pancreatic Intraductal Oncocytic Papillary Neoplasm to the Ovaries
Emily Fronk1, Jamie McDowell2, Natalia Yanchenko3
1Department of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Avenue Box 668, Rochester 14642, New York, USA, rochester.edu.
Objectives:
Intraductal oncocytic papillary neoplasm (IOPN) is a digestive system tumor typically found in the head of the pancreas. Most often, they remain confined to the pancreas; it is rare that they develop into an invasive carcinoma or metastasize.
Methods:
This paper presents the case of a 63-year-old postmenopausal female with a past medical history notable for BRCA1 mutation and exploratory laparotomy with pancreatoduodenectomy who underwent risk-reducing laparoscopic bilateral salpingo-oophorectomy.
Results:
Postoperative pathology revealed metastatic oncocytic papillary neoplasm involving the bilateral ovaries. She was ultimately referred to gastrointestinal medical oncology for further management.
Conclusions:
This is the first report to our knowledge of pancreatic IOPN metastasizing to the ovaries. It is essential for cases to be reported for guidance of treatment regimens.
Related Concept Videos
Oogenesis
Ovaries
On the ovarian surface, a layer of cuboidal...
Ovarian Cycle

