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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
Published on: July 29, 2022
Infectious Acute Pancreatitis: Salmonella Typhimurium
Preskila Gurung1, Julius Nwajei1, Uchechukwu Obiagwu2
1Acute Medicine, William Harvey Hospital, Ashford, GBR.
Abstract:
Acute pancreatitis is most commonly attributed to gallstones or alcohol consumption. Infectious etiologies remain rare and are often overlooked. Salmonella enterica typically presents as self-limiting gastroenteritis, but it can occasionally lead to severe systemic complications. We report a case precipitated by S. enterica serotype Typhimurium in a 48-year-old male returning from North Africa. History-taking, physical examination, and investigations ruled out common biliary and metabolic causes and confirmed Salmonella infection. The patient was treated with intravenous antibiotics and supportive care, leading to significant clinical and biochemical improvement. This case highlights the importance of clinicians maintaining a high index of suspicion for infectious causes of pancreatitis, particularly in patients with a relevant clinical history.
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Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
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