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Updated: Sep 22, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
Published on: November 3, 2014
Transcriptomic profiling of murine macrophages during Francisella tularensis infection
Ma'ayan Israeli1, Inbar Cohen-Gihon1, Ofir Israeli1
1Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel.
Abstract:
Francisella tularensis, a virulent bioterrorism threat, subverts host immune responses within macrophages, its primary replication niche. To elucidate the temporal dynamics of the host response, we announce comprehensive time-course RNA-seq data sets capturing the global transcriptional profile of murine RAW 264.7 macrophages across early and late stages of F. tularensis infection.
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