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Updated: Sep 22, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
Published on: June 20, 2014
Double photooxygenation of C-H bonds for the synthesis of polyoxygenated molecules
Ben C Bimberg1, Jonas Morast1, Axel Jacobi von Wangelin1
1Department of Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany. axel.jacobi@uni-hamburg.de.
Abstract:
Double photooxygenation of hydrocarbons with O2 enables rapid access to oxygenated scaffods. Two consecutive allylic oxidations operate at one double bond in a flow reactor with high atom economy and selectivity. The resultant dihydroperoxides constitute functional building blocks with distinct properties as energetic materials and precursors to polyols and epoxides.
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