Related Experiment Video
Updated: Sep 24, 2026

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
Published on: September 26, 2016
Context-aware diffusion models for solving partial differential equations
Bosi Guo1, Chunyan Xu1, Shuaizhen Yao1
1School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China.
Abstract:
Solving partial differential equations (PDEs) enables computers to simulate and understand continuously evolving physical processes in nature, forming a critical foundation that bridges physical laws and intelligent computation. Recently, deep learning has emerged as a research hotspot for solving PDEs due to its powerful nonlinear representation capacity and efficient approximation capabilities. However, it still faces challenges such as poor generalization and unsatisfactory solution accuracy. To this end, this paper proposes a context-aware diffusion model-driven framework for solving differential equations. First, we establish an implicit denoising diffusion mechanism tailored for solving differential equations. Second, we integrate contextual information, which includes demonstration data (i.e., known condition-solution pairs) and the current problem conditions, into the denoising network through a cross-attention mechanism. This integration provides precise guidance for solution generation throughout the recursive denoising process. Experimental results are reported across three categories of differential equation problems: linear, nonlinear, and variational problems. Our method demonstrates competitive or superior solution accuracy compared with representative neural operator baselines, including FNO, DeepONet, ICON, OFormer, UNO, and GNO.
Related Concept Videos
Diffusion
Diffusion
Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Modeling with Differential Equations
Partial Differential Equations

