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Updated: Sep 24, 2026

Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing
Published on: August 25, 2018
When current taxids make historical taxa look new
1Nantes, France.
Abstract:
A taxon can keep its biological identity while its numeric identifier changes over time. Reconstructing a past taxonomy state by resolving each sequence to its current-day identifier ignores this and can make an already-existing taxon look newly created. Among 56 viral sequences flagged as newly created between two NCBI taxonomy snapshots one year apart, only 17 (30.4%) were genuinely absent from the earlier snapshot; the remaining 39 (69.6%) already existed there under a predecessor identifier later merged into today's. The same mechanism recovers 222-272 identifiers per snapshot across an independently drawn library-wide population of 14,607 identifiers, for 10 of 13 dated snapshots studied (2014-2022). An illustrative classification experiment shows the practical consequence: retagging the 39 artifacts with their period-valid identifier restores correct classification. Since correction relies on identifier-merge history alone, it establishes apparent novelty caused by identifier evolution, not biological novelty. We give five recommendations to avoid this artifact.
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