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Recent Advancements in Cancer Diagnosis via Spectroscopic Analytical Techniques
Shanza Poswal1, Bushra Naureen1, Usman Shareef1
1Department of Pharmaceutical Chemistry, Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Abstract:
Spectroscopic methods offer vital information on the molecular makeup, interactions, and structure of biological tissues by examining the relationship between matter and electromagnetic radiation. Conventional diagnostic procedures frequently have limitations, and early diagnosis of cancer is critical for improving patient outcomes. The purpose of this review article is to investigate the possible uses of several spectroscopic methods in the diagnosis of cancer, with an emphasis on breast cancer, cervical cancer, colorectal cancer, brain tumors, ovarian cancer, abdominal cancer, prostate cancer, lung cancer, ovarian cancer and esophageal cancer. An extensive overview of spectroscopic methods, such as nuclear magnetic resonance (NMR), mass spectrometry, infrared spectroscopy, and Raman spectroscopy, are explored for applications in the diagnosis of cervical, colorectal, gastric, breast and prostate malignancies. Spectroscopic methods have several benefits, including high sensitivity for identifying cancer biomarkers, noninvasiveness, and real-time findings. These techniques are becoming more and more useful for diagnosing breast cancer since they make it easier to grade tumors, classify malignancies early, and determine certain biomarkers. For these approaches to be used in clinical settings, assay development, automation, and collaborative study development are crucial. Although there are some difficulties, continuous developments in spectroscopy can hold the potential to revolutionize cancer detection and enhance patient care.