[Collaborative innovation in devices and methodology propels cardiovascular interventional occlusion into a new era]

The development of cardiovascular interventional therapies has always been closely linked to synergistic innovation in devices, materials, and methodologies. Taking occlusion technique as an example, traditional metal occluders have a fixed shape and are relatively rigid; their inadequate morphological and mechanical adaptation to the dynamic structure of the heart may affect patients' long-term prognosis. This article reviews biodegradable occluders and magnetofluid-based in situ adaptive shaping technique, exploring the progress and challenges in the field of interventional occlusion regarding device design, material systems, and tissue repair concepts, and discusses the methodological value of ultrasound-guided intervention in the translation of novel materials and non-metallic devices. In the future, it will be necessary to deepen our understanding of these topics, strengthen multidisciplinary collaboration and the development of clinical translation platforms, and drive cardiovascular interventional occlusion therapy toward greater precision, lower physiological burden, evidence-based practices, and scalable technologies.