Related Experiment Video
Updated: Sep 26, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Mitigating and Anticipating Periprocedural Risks of Transcatheter Pulmonary Valve Replacement in the Elderly
Jennifer N Adouli1, Arash Salavitabar2, Konstantinos Dean Boudoulas3
1Department of Internal Medicine, The Wexner Medical Center at The Ohio State University, Columbus, Ohio, USA.
Background:
Transcatheter pulmonary valve replacement (TPVR) has a different complication profile than surgical pulmonary valve replacement, and consensus guidelines on this topic are lacking.
Case Summary:
We describe a case of an 81-year-old man who underwent balloon valvuloplasty and TPVR for pulmonary stenosis and regurgitation. A guidewire was placed across a prior coronary stent in the left anterior descending artery during balloon valvuloplasty. Following TPVR, he developed acute diastolic heart failure, a delayed pericardial effusion, and suspected infective endocarditis.
Why Beyond The Guidelines:
Peri and postprocedural complications are not addressed in guidelines.
Discussion:
We discuss strategies to identify and address peri and postprocedural TPVR complications.
Take-Home Message:
Through a proactive approach, peri and postprocedural TPVR complications can be managed successfully.
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