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Clinical Outcomes and New Treatments in Pediatric Brain Tumors

Craig Erker1,2, Sébastien Perreault3

  • 1Division of iHOPE, Department of Pediatrics, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Current Oncology (Toronto, Ont.)
|September 24, 2026
PubMed

Abstract:

Central nervous system (CNS) tumors represent the most common solid tumors of childhood and remain the leading cause of cancer-related mortality among pediatric patients [...].

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

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