Related Experiment Video

Updated: Sep 26, 2026

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor
09:33

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

Published on: August 25, 2023

Therapeutic Vulnerabilities of the Key Genetic Drivers in Leiomyosarcoma

Ekaterina A Lesovaya1,2,3, Timur I Fetisov1, Beniamin Yu Bokhyan1

  • 1Laboratory of Molecular Mechanisms of Chemical Carcinogenesis, Institute of Experimental Oncology and Carcinogenesis, N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia, 24 Kashirskoe Shosse, Moscow 115478, Russia.

Medical Sciences (Basel, Switzerland)
|September 24, 2026
PubMed

Keywords:
amplificationchromosomal translocationepigenetic changesgenetic heterogeneitygenome instabilityimmunotherapyleiomyosarcomamutationsignaling alteration

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