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Updated: Sep 26, 2026

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
14:02

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

Photocaging of a GPR52 agonist enables light-dependent receptor activation in cells

Wen Ren1, Yuexin Liu2, Xiaoyan Dai1

  • 1School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen 518132, China.

Bioorganic & Medicinal Chemistry Letters
|September 24, 2026
PubMed

Keywords:
Biological evaluationCellular irradiationGPCRGPR52PhotoactivationPhotocaged agonist

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