Related Experiment Video
Updated: Sep 26, 2026
Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder
Published on: July 7, 2023
A network analysis of core symptoms in menopausal syndrome
Huan Wu1, Danfeng Gao1, Liwen Song1
1Obstetrics and Gynecology Department, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background:
Menopausal symptoms are common during the menopausal transition and can substantially affect women's physical and psychological health. These symptoms often co-occur and interact, but their complex interrelationships and the symptoms that play central roles within the symptom network remain unclear.
Objective:
Explore the network structure of menopausal syndrome and identify core symptoms.
Methods:
A cross-sectional study of 402 perimenopausal women aged 40-60 years in Shanghai, China, November 2023 to April 2024. The Greene scale was used for evaluation. Perform a network analysis to identify core symptoms.
Results:
Irritability, fatigue and hot flashes were the highest central values in the menopausal symptom network, indicating that they were the core symptoms.
Conclusions:
Irritability, fatigue and hot flashes were identified as central symptoms in the menopausal symptom network. These findings may inform clinical symptom assessment and future research on symptom management.
Related Concept Videos
01:28Menopause
01:22Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
01:19The Menstrual Cycle
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a uterine...
01:27Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
01:27Depressive Disorders: MDD and Dysthymia
01:30Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...