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Published on: April 16, 2018
Dietary melatonin and its benefits on cardiovascular disease
Karabo Tisane1, Carmelita Abrahams1, Sandrine Lecour1
1Cardioprotection Group, Cape Heart Institute, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Abstract:
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low- and middle-income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti-inflammatory and immunomodulatory properties that may confer cardiovascular benefits. Importantly, melatonin is also found in a wide range of dietary sources, raising the possibility that regular consumption of melatonin-rich foods could offer a low-cost, accessible strategy to support cardiovascular health. This review summarises knowledge on dietary melatonin and evaluates its potential to provide cardiovascular benefits.
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