Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps
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Updated: Sep 26, 2026
Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
Published on: August 25, 2022
Dakota de Cecco1, Jeanne du Fay de Lavallaz1, Boldizsar Kovacs2
1Electrophysiology Section, Division of Cardiology, University Hospital of Michigan, Ann Arbor, Michigan, USA.
Abstract:
Pulsed field ablation (PFA) has rapidly emerged as an important ablation technology for atrial arrhythmias and is increasingly being explored for ventricular arrhythmias. As clinical experience expands, a precise understanding of its safety profile is essential. This review summarizes contemporary evidence on the safety of PFA, distinguishes procedure-related complications from those attributable to electroporation, and highlights areas in which evidence remains limited.
