Related Experiment Video
Updated: Sep 27, 2026

Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
Quality Evaluation Research Based on Functional Component Group and Quality Control Coefficient: A Case Study of
Pei Chen1, Qinqin Zhang1, Conglong Lian1,2
1College of Pharmacy, Henan University of Chinese Medicihne, Zhengzhou 450046, China.
Abstract:
Quality is critical to the market competitiveness of medicinal and edible GF. However, the current quality standards of the Chinese Pharmacopoeia rely on a single index and cannot comprehensively evaluate food material with diverse origins and multiple functional components. This study established a holistic evaluation strategy based on "functional component group" and "quality control coefficient Q". Seven stable fingerprint peaks of iridoids and iridoid glycosides were identified by chromatography, with Q ≥ 3.67 as the quality benchmark. In cell experiments, HQG outperformed QG in the MTT assay of LPS-stimulated RAW264.7 cells. In addition, 78 volatile compounds and 22 inorganic elements were analyzed by GC-MS and ICP-MS, respectively, as complementary analyses. Combined with chemometrics, the samples were discriminated according to geographical origin and tissue, and characteristic markers were screened on an exploratory basis. This study provides a scientific basis for precise quality control and screening of high-quality GF, and offers a reference framework for quality evaluation of other medicinal and edible homologous plants.
Related Concept Videos
Quality Control
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
Factors Affecting Workability
Quality Assurance
Qualitative Analysis
For instance, group IV...
Qualitative Analysis
There are two main approaches to qualitative analysis:...
Quality of Water