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Updated: Sep 28, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Application of Shen's New Technical System in Meek micrografting for patients with extensive burns: A retrospective
Hu Hang1, Yiran Wang1, Hongfei Jiang2
1Department of Burns & Wound Care Centre, The Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, China; The Key Laboratory of the Diagnosis and Treatment of Severe Trauma and Burn of Zhejiang Province, Hangzhou, China.
Background:
Extensive burns pose a severe clinical challenge where surgical closure must be synchronized with physiological support to ensure survival. Although Meek micrografting improves wound coverage, patients remain vulnerable to systemic complications. This preliminary exploratory study aimed to examine clinical outcomes associated with the implementation of "Shen's New Technical System for Critical Burn Treatment" in patients with extensive burns undergoing Meek micrografting.
Methods:
We conducted a retrospective pilot cohort study with historical controls involving ten patients with extensive burns(>50% TBSA) treated between 2021 and 2025. Patients were stratified into a Control Group (n = 5) receiving standard care and a New Technology Group (n = 5) managed under the new technical system. Intergroup differences were evaluated for treatment efficiency including hospital length of stay (LOS) and total costs alongside clinical parameters including residual wound area at one month, catheter utilization, infection rates, nutritional support utilization, and gastrointestinal complications.
Results:
No statistically significant differences were observed in the measured baseline characteristics between the two groups (all P > 0.05). The New Technology Group demonstrated a greater than 50% reduction in hospital LOS (40 ± 15 vs. 86 ± 25 days, P = 0.010) and a substantial decrease in total hospitalization costs (0.49 ± 0.31 vs. 1.46 ± 0.75 million RMB, P = 0.042). The New Technology Group had a smaller residual open wound area at one month (4 ± 4% vs. 37 ± 8% TBSA, P < 0.001). Furthermore, the New Technology Group had significantly fewer total deep vein catheters (P = 0.008), positive deep vein catheter cultures (P = 0.043), positive blood culture episodes (P = 0.029), and diarrhea occurrences (P = 0.007).
Conclusions:
Shen's New Technical System was associated with shorter hospital stays, lower hospitalization costs, faster wound closure, and fewer catheter-, infection-, and gastrointestinal-related complications in patients undergoing Meek micrografting, suggesting potential advantages in improving overall rescue efficiency for extensive burns.
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