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Characterisation of Two Novel HLA Class II Null Alleles: DRB1*14:294N and DQB1*03:611N

Miguel Angel Moreno-Hidalgo1, Andres Roncancio-Clavijo1, Iris Vicente1

  • 1Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain.

HLA
|September 27, 2026
PubMed

Keywords:
HLA class IINGSnull alleles

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For the same gene multiple alleles can interact to influence phenotypes like the shape and protein composition of an individual cells.By studying allele interactions on the molecular and cellular levels researchers can understand the resulting phenotypes and complications of human conditions like sickle cell trait, improving treatment.The ABO blood group system is a common example of multiple alleles in humans. This system includes three alleles called IA, IB, and i alleles, which combine in...