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Updated: Sep 30, 2026

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Protein engineering of formolase for the synthesis of 1,3-dihydroxyacetone from formaldehyde

Zijian Tan1, Ruke Zhang1, Haifeng Liu2

  • 1Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, P.R. China.

Methods in Enzymology
|September 28, 2026
PubMed

Keywords:
1,3-DihydroxyacetoneFormaldehydeFormolaseHigh-throughput screeningProtein engineeringSaturation mutagenesisSubstrate channelTPP-dependent enzyme

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