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Updated: Sep 30, 2026

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach
Published on: June 23, 2026
Microwave-assisted combinatorial synthesis of phalloidin derivatives for optimization of
Tino Damaszek1, Mark A R de Geus2, Zhanyu He1
1Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin, Germany. suessmuth@chem.tu-berlin.de.
Abstract:
A microwave-assisted approach enables the rapid synthesis of a comprehensive library of phalloidin derivatives. Actin polymerization assays reveal several compounds that exhibit an enhanced rate of F-actin polymerization compared to the native toxin.
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