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Updated: Oct 1, 2026

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Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy
Published on: September 8, 2009
Single-molecule fluorescence methods for visualizing the central dogma
Jailynn Harke1, Melike Lakadamyali2
1Department of Physiology, Perelman School of Medicine, University of Pennsylvania, United States.
Current Opinion in Structural Biology
|September 29, 2026
Abstract:
Fluorescence microscopy has long been a powerful tool for observing biological phenomena inside cells and tissues. Here, we discuss recent advances in fixed and live-imaging approaches to visualize the central dogma at the single-molecule level.

