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Updated: Oct 1, 2026

Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain
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Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain

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The YTHDF proteins modulate Alzheimer's disease-associated brain gene signatures

Shinya Tasaki1, Denis R Avey2, Nicola A Kearns2

  • 1Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA. stasaki@gmail.com.

Molecular Neurodegeneration
|September 30, 2026
PubMed

Keywords:
Alzheimer's diseaseCRISPR knockoutCognitive declineCortical organoidsEpitranscriptomicsGene expression signaturesMachine learningPost-transcriptional regulationSmall-molecule YTHDF inhibitioneCLIP-seq

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