Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pilosebaceous abnormalities in Apert type acrocephalosyndactyly.

L M Solomon, M M Cohen, S Pruzansky

    Birth Defects Original Article Series
    |June 1, 1971
    PubMed
    Summary

    Forearm acne, characterized by comedones and pustules, is rare in the general population. However, it was observed in over 70% of Apert syndrome patients, indicating potential links to steroid sensitivity and androgen disposition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Determination and correlation of in vitro viability for hairless mouse and human neonatal whole skin and stratum corneum/epidermis.

    Archives of dermatological research·1997
    Same author

    What syndrome is this? Papillon-Lefevre syndrome.

    Pediatric dermatology·1994
    Same author

    Cephalic pyoderma gangrenosum (PG)-like lesions as a presenting sign of Wegener's granulomatosis.

    International journal of dermatology·1994
    Same author

    Evaluation of transdermal theophylline pharmacokinetics in neonates.

    Pharmacotherapy·1993
    Same author

    Confirmation of an oroacral pattern of anomalies: a disruption?

    American journal of medical genetics·1992
    Same author

    Bannayan-Riley-Ruvalcaba syndrome.

    American journal of medical genetics·1992

    Area of Science:

    • Dermatology
    • Genetics
    • Endocrinology

    Background:

    • Forearm acne, including comedones and pustules, is typically rare in the general population.
    • Apert syndrome is a genetic disorder associated with distinct craniofacial and limb abnormalities.

    Purpose of the Study:

    • To investigate the prevalence and characteristics of forearm acne in patients with Apert syndrome.
    • To explore potential underlying mechanisms contributing to forearm acne in Apert syndrome.

    Main Methods:

    • Observational study of Apert syndrome patients.
    • Clinical assessment of forearm acne presentation.

    Main Results:

    • Forearm acne was identified in over 70% of evaluated Apert syndrome patients.
    • The observed prevalence significantly exceeds that in the general population.

    Conclusions:

    • Forearm acne is a common manifestation in Apert syndrome.
    • Steroid sensitivity and androgen tissue disposition are potential avenues for further research in Apert syndrome pathogenesis.

    Related Experiment Videos