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Updated: Oct 2, 2026

Measurement of Natural Killer Cell-Mediated Cytotoxicity and Migration in the Context of Hepatic Tumor Cells
Published on: February 22, 2020
Natural Killer Cells and Innate Lymphoid Cells Immunoprofiling
Christelle Piperoglou1, Frédéric Vély2,3
1APHM, Hôpital de la Timone, Marseille Immunopole Profiling Platform, Marseille, France.
Abstract:
Phenotyping of natural killer (NK) cells by flow cytometry allows a detailed analysis of their functional diversity and activation status. This multiparametric approach assesses the expression of activating or inhibitory receptors and detects markers of maturation or exhaustion. It is crucial for understanding the role of NK cells in the immune response, particularly against infections and tumor cells. This phenotyping also allows us to monitor the effects of immunomodulatory treatments and to identify prognostic or predictive biomarkers in different clinical contexts.
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