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An Unexpected Cause of Severe Steatohepatitis in a Young Male
Longfeng Jiang1, Zixing Dai1, Chuanlong Zhu2
1Department of Infectious Diseases, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Question:
A 24-year-old male with a body mass index (BMI) of 37.4 kg/m2 was referred to our hospital following the incidental discovery of abnormal liver echogenicity on a routine physical examination. The patient denied any history of alcohol consumption or illicit drug use and reported no family history of liver or metabolic diseases. Abdominal ultrasonography performed in December 2025 revealed heterogeneous liver echotexture with diffuse nodular hyperechoic areas, initially suggestive of nodular fatty infiltration or cirrhosis, and was accompanied by mild splenomegaly. Contrast-enhanced abdominal computed tomography (CT) demonstrated the following findings (Figure A).
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