Ocular Adipostructuring in Complications From Orbital Fillers: Managing the Orbital Base

The periocular contour is one of the most complex and vulnerable anatomical regions of the face and is highly prone to complications following the injection of biomaterials such as liquid polycaprolactone (PCL), hyaluronic acid (HA), and polylactic acid (PLA). These complications include persistent hyperpigmentation, malar edema, fibrosis, sensation of pressure, structural irregularities, and lymphatic dysfunction. Periocular adipostructuring is a specialized variant of facial adipostructuring. The technique uses blunt-tipped cannulas (25G and 27G × 50 mm), precise maneuvers for controlled tissue dissection, and localized delivery of the active components of the FaceStructure® Kit (Mioface Harmony, Cúcuta, Colombia), together with adjuvant agents such as Melilotus officinalis and organic silicon. Through this approach, fibrosis is released, mechanotransduction is activated, the clearance of ferric pigments is promoted, and lymphatic drainage is stimulated, thereby restoring the anatomical architecture without inducing additional volume or trauma. This is a retrospective experimental study in which 30 patients presenting with clinical complications of the periocular region secondary to the placement of PCL, PLA, and HA fillers were treated, distributed as follows: PCL = 12; PLA = 10; and HA = 8. The study included 22 females and eight males aged between 35 and 60 years. The results show that, despite involving complications in the periocular contour, most patients achieved clinical recovery, and the treatment was associated with a histological shift consistent with the remodeling of localized fibrosis into a more organized and functional dermal tissue. Using this technique in complicated patients has allowed the development of a functional regenerative intervention model focused on restoring optimal anatomical conditions so that the tissue can recover autonomously, providing a reproducible, safe solution that is applicable to a broad spectrum of complications.