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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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A machine learning method for calculating highly localized protein stabilities

Chenlin Lu1, Kyle C Weber1, Savannah K McBride1

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Nature Communications
|October 1, 2026
PubMed

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