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Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
Published on: August 30, 2013
Locate Then Classify: A Heterogeneous Dual-Teacher Consensus Framework for Semi-Supervised Mammogram Diagnosis
Xiaowen Tang1, Siyu Wang2, Haiyan Wang1
1Department of Radiology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42, 42 Baiziting, Nanjing, 210009, China.
Abstract:
Semi-supervised learning (SSL) offers a pathway to reduce the high cost of pixel-wise annotation in mammography, but classical teacher-student methods suffer from confirmation bias under extreme label scarcity. To address this, we propose a heterogeneous dual-teacher consensus framework (DTSL). Two complementary teachers, one detail-oriented (shallow SE attention) and one semantic-oriented (deep gated modulation), retain pseudo-labels only when they agree, thereby filtering unreliable predictions. Using only 30% of pixel-level labels, DTSL recovers 81.5% of fully supervised segmentation performance (Dice Similarity Coefficient, DSC = 0.626) and achieves a calcification intersection over union (IoU) of 0.700, reducing annotation cost by 70%. It outperforms standard Mean Teacher (78.1%) and nnU-Net plus Mean Teacher (79.8%). The trained segmentation encoder is then transferred to a classification head, injecting morphological priors into malignancy diagnosis. On the INbreast dataset, our classifier attains an AUC of 0.872 and a sensitivity of 0.837, surpassing the average sensitivity of four senior radiologists (0.803) by 3.4 percentage points (p < 0.05). Our model's superior sensitivity suggests its potential as a decision-support tool to reduce false negatives in screening, warranting prospective clinical validation. Grad-CAM visualizations confirm that attention maps align with radiologists' diagnostic cues. The source code is available at https://anonymous.4open.science/r/BrXNetCls-0C14/ .