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Updated: Oct 7, 2026

Identification of Plasmodesmal Localization Sequences in Proteins In Planta
Published on: August 15, 2017
Nucleocytoplasmic trafficking of immune signals in plants
Weiyi Dou1, Fenghui Xu1, Xinyi Cai1
1Shanghai Engineering Research Center of Plant Germplasm Resources, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai 200234, China.
Abstract:
The nuclear pore complex (NPC) was initially viewed as a passive gateway for molecular transport, but it is now recognized as an active and highly selective signaling hub that orchestrates nucleocytoplasmic communication. In plants, dissection of the NPC's intricate architecture has revealed its critical role in innate immunity: specific nucleoporins selectively gate the nuclear entry of key immune regulators, while plant‑specific components dynamically control pore permeability or form phase‑separated condensates that assemble specialized transcription factories. Strikingly, the NPC recruits cell cycle, RNA processing, and chromatin‑modifying complexes into higher‑order "complexes" that coordinate defense activation with development, RNA metabolism, and epigenetic memory. This emerging paradigm positions the NPC as a central integration platform, opening new opportunities for engineering disease‑resistant crops.
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