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Updated: Oct 7, 2026

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach
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Engineering the α-Helix Dynamics of Hydroxysteroid Dehydrogenase by Computational Design to Balance Catalytic

Shu-Fang Li1,2,3,4, Ting Zou1,2,3,4, Sen-Yu Fu1,2,3,4

  • 1State Key Laboratory of Green Chemical Synthesis and Conversion, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.

Biotechnology and Bioengineering
|October 6, 2026
PubMed

Keywords:
catalytic activitycomputational‐guided designhydroxysteroid dehydrogenasethermostabilityα‐helix dynamics

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