Studies on the buckwheat allergose report 1: on the cases with the buckwheat allergose

In this report 9 cases with the buckwheat allergose treated and observed in our allergy clinic are summarized. The following is to be specially mentioned as the most distinguishing traits of the buckwheat allergose. 1) Among such hypersensitive manifestations with buckwheat as asthmatic attacks, urticaria eruption, gastrointestinal disorders, nasal symptoms or congestion of conjunctiva, the boundary line cannot be drawn. 2) The manifestation develops both when the allergen substance invades into the body through mouth and when through air way. 3) Judging from the results of various kinds of allergic examination, the hypersensitive manifestations are attributed to the allergic mechanism based on the antigen-antibody reaction in the strict sense of the word. And the buckwheat allergose is considered to be the model of the type 1 allergy (that is immediate type allergy) proposed by Coombs and Gell. 4) The antigenity of buckwheat is extremely strong, and the hyposensitization treatment with buckwheat must not easily be applied for fear of a severe and dangerous reaction due to the injection of the buckwheat extract.