Related Experiment Video

Updated: Oct 7, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

Cell-based polygenic risk scores predict clinical progression and prioritize network-based therapeutic targets in

Nathan Sahelijo1,2, Priya Rajagopalan3,4, Lu Qian5

  • 1Biomedical Genetics Section, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|October 6, 2026
PubMed
Abstract

Keywords:
Alzheimer's diseasePageRank algorithmcell‐based polygenic risk scorecell‐level co‐expression networkcognitive performancedrug repurposingpatient stratificationprecision medicine

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