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Updated: Oct 9, 2026

Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network
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Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network

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Periodontitis GWAS Reveal Immune-Biased Heritability Without Gingival Cell-Type Resolution

Chengze Wang1, Wenyue An1, Mengna Lin1

  • 1Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.

Journal of Periodontal Research
|October 7, 2026
PubMed

Keywords:
GWAS powerheritabilityperiodontitissingle‐cell

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...